Cannondale's Domestique Shorts are made of their breathable Miti Nova 2.1 fabric. They boast an 8-panel fit that actually relieves fatigue by supporting your muscles so you can ride stronger longer. For outstanding comfort, Cannondale's Cytech-EIT Fiandre Air chamois has padding in all the right places. These fine shorts also feature Lean and Clean cuffs that grip your legs without the traditional silicone grippers.
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My favorite pair of bike shorts that I own.